Ibogaine interrupts opioid addiction at its neurological root — dramatically reducing withdrawal, resetting receptor sensitivity and opening the neuroplastic window within which lasting recovery becomes possible. Withdrawal symptoms often near-disappear within 12–24 hours.

Opioids hijack the brain's reward system with a precision that no other class of drugs matches. They bind to mu, kappa and delta opioid receptors throughout the brain and nervous system, rapidly producing physical dependency. The withdrawal that follows cessation is not weakness — it is the neurological consequence of receptor adaptation.
Conventional treatment replaces one opioid with another — managing dependency rather than ending it. Ibogaine does something fundamentally different: it resets opioid receptor sensitivity toward pre-addiction baselines, dramatically shortening and reducing withdrawal while opening the neuroplastic window within which genuine recovery becomes possible.
"After 8 years of opioid addiction and four failed rehabs, ibogaine at Amari reached somewhere nothing else could. I left a fundamentally different person."
— Michael T., 34 · Opioid Recovery · United StatesIncluding both street and pharmaceutical fentanyl. Fentanyl dependency typically requires our 10-day Extended Programme for adequate stabilisation.
Oxycodone, hydrocodone, morphine, codeine and other prescribed opioids that have produced physical dependency.
Possible with specific tapering protocols prior to treatment. Our team guides you through this process. Typically requires the Extended Programme.
Full medication disclosure required. Our team will assess suitability and design the appropriate protocol during intake.
Ibogaine's action on opioid addiction works through multiple complementary mechanisms — each contributing to the interruption of dependency.
Ibogaine resets mu, kappa and delta opioid receptor sensitivity toward pre-addiction baselines — explaining why withdrawal symptoms dramatically reduce within 12–24 hours of a flood dose.
Opioid addiction dysregulates dopamine signalling, creating the anhedonia and craving of early recovery. Ibogaine modulates dopamine transporters, helping restore natural dopamine baseline.
Ibogaine increases GDNF production — a protein that promotes restoration of dopaminergic neurons in the brain regions most damaged by prolonged opioid use.
Ibogaine metabolises to noribogaine — active for days to weeks — sustaining the neuroplasticity window in which cravings are reduced and new habits can be established.
Individual results vary. Methadone/suboxone require specific tapering protocols.
Full medical intake including ECG, blood panel and liver function. Medication review and tapering protocol planning where needed. Pre-treatment preparation with your psychologist. Somatic bodywork to stabilise your nervous system.
Flood dose under continuous cardiac monitoring with Dr. Campos present. Three phases: visionary (4–8 hours), mental processing, and recovery. Withdrawal symptoms typically reduce dramatically within 12–24 hours. Round-the-clock nursing support.
Nourishment, hydration and rest. Daily integration with your psychologist. Therapeutic massage and somatic therapy for nervous system recovery. Introduction to 30-day aftercare including group calls, 1:1 coaching and the 10 Pillars framework.
Methadone and buprenorphine have long half-lives and complex interactions with ibogaine. A medically supervised tapering protocol is required. This typically extends to our 10-day Extended Programme. Our clinical team will guide you through every step. Please do not attempt to taper without medical supervision.
Speak with our team about your situation →Ibogaine's QT prolongation risk demands specialist oversight. Dr. Rogelio Campos Ortega, our board-registered cardiothoracic surgeon, is present for every ibogaine administration.
12-lead ECG and blood panel reviewed by Dr. Campos Ortega before treatment proceeds.
ECG telemetry throughout. Vital signs, blood pressure and oxygen saturation monitored by nursing staff.
Intravenous access maintained throughout. Magnesium, sodium, calcium and potassium actively managed.
Free, confidential consultation. Honest assessment of whether ibogaine is right for your specific substance history and medications.
+52 984 166 1833 · contact@amariboga.com · Riviera Maya, México